Arthritis is derived from the Greek: “arthron” meaning “joint” and “itis” meaning inflammation. Osteoarthritis is a type of arthritis. When knee is affected by osteoarthritis is known as knee osteoarthritis. Many treatments are available; none is universally safe and effective. Therefore, there is need to prepare polyherbal formulations to provide safe and effective treatment. This study was conducted to assess the efficacy and safety of Osteoarthritis capsule and Oil. These formulations, in patients with knee osteoarthritis. This was 3 months, open-labelled study of these formulations in 19 patients suffering from knee osteoarthritis. Patients received 2 capsules twice daily and Oil to be applied over the knee once times in a day for 3 months. The efficacy was evaluated on the basis of knee osteoarthritis parameters like severity of pain, joint swelling, muscle rubbing, morning stiffness, difficulty in climbing steps, no. of joints involved, joint space. 19 patients completed the study with reduction in symptoms of knee osteoarthritis to varying degrees. Statastical analysis was done by paired‘t’ test. At end of , month 1, 2 and 3, mean score of severity of pain had a fall of 2.36,1.35,0.73 ,joint swelling had a fall of 1.41, 0.68,0.10, muscle rubbing had a fall of 1.42, 0.73, 0.26, morning stiffness had a fall of 1.63, 0.89, 0.36 ,difficulty in climbing steps had a fall of 1.79,1, 0.26, no. of joints involved had a fall of 2.57, 1.31,0.36, joint space had a fall of 0.47, 0.51, 0.55 respectively.. This study confirms the efficacy and safety of these formulations in Indian patients with knee osteoarthritis.
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